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A guide to sequencing of large genomes with Oxford Nanopore

17th May 2019

Even though the sequence of the well-studied human genome was published over a decade ago, it is still incomplete. Large eukaryotic genomes are a challenge to sequence and assemble with short reads; nanopore long reads enhance large genome assembly.

Full characterisation of plant and animal genomes via high-throughput sequencing is revolutionising many areas of research. In human and veterinary health, sequencing enables unprecedented insights into disease, whilst investigating genetic variation in plants allows for the maintenance of diversity and selection of desirable traits, such as high yield and resistance to pathogens. Whole genome sequencing also helps shed light on the evolutionary relationships between organisms.

Long-read sequencing with Oxford Nanopore simplifies genome assembly. Download our Getting Started guide for sample-to-answer guidance on whole genome sequencing of large genomes with Oxford Nanopore.

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