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Nanopore sequencing offers advantages in all areas of research. Our offering includes DNA sequencing, as well as RNA and gene expression analysis and future technology for analysing proteins.

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MinION GridION PromethION Flongle VolTRAX
PromethION high-throughput nanopore sequencing device

Large-scale, long-read, direct DNA and RNA sequencing

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Terabases of data

1 - 48 flow cells

Flexible, on-demand sequencing

High-performance compute

Analyse data in real time

Up to 14 Tb data*

Population-scale sequencing

* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.

Why PromethION?

PromethION high-throughput nanopore sequencing device

On-demand sequencing

Run up to 48 independently addressable, high-capacity PromethION Flow Cells.

Ultra-high throughput

Generate terabases of data — streamed in real time for immediate analysis.

Powerful compute

Alleviate data analysis bottlenecks.

Population-scale sequencing

Generate sub-$1,000 human genomes.

No capital cost

Pay just for consumables.

Nanopore Service Certification

Service provider certification is available for PromethION

Find out more

Solving Ohno’s puzzle — resolving an ancient sex chromosome system

Matthew Brian Couger at Brigham and Women’s Hospital, USA, and coworkers use ultra-long sequencing reads delivered by PromethION to solve a 60-year old puzzle.

Read more

100 tomato genomes in 100 days

Researchers at Johns Hopkins University utilise PromethION to reveal substantial genomic variation between tomato plants, including a tandem duplication associated with higher fruit yield.

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Accessing the inaccessible human genome with long reads

Discover how Shafin and colleagues used PromethION to sequence 11 human cell lines in just 9 days.

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Specifications

PromethION is available in two models: PromethION 24 (P24) and PromethION 48 (P48), which can respectively operate up to 24 and 48 flow cells at once.

Read length

Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >4 Mb)

Dimensions

Compact benchtop device with compute module

Sequencing module:

  • Size: W 590 mm, H 190 mm, D 430 mm
  • Weight: 28 kg

Compute module:

  • Size: W 178 mm, H 440 mm, D 470 mm
  • Weight: 25 kg

Up to 290 Gb per flow cell*

Total device yield as much as:

  • Up to 7 Tb PromethION 24*
  • Up to 14 Tb PromethION 48*

* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.

Suitable applications

  • Larger genomes or projects
  • Population-scale sequencing
  • Highly multiplexed small genomes or targeted regions
  • Whole transcriptomes (direct RNA or cDNA)

On demand

Sequence what you need, when you need it

  • Run flow cells individually or together — no more sample batching
  • Each flow cell has approximately six times the sequencing capacity of a MinION Flow Cell
  • Run multiple DNA or RNA experiments at once
  • Barcode for even more samples
  • Suitable for high-throughput and service labs

Accessible

  • No capital cost
  • Small footprint — suitable for any lab
  • Easy installation with comprehensive support

High-performance compute

Sequencing and analysis in one powerful device

  • Latest generation CPU for OS and orchestration
  • State-of-the-art basecall accelerators
  • 32 TB (P24) or 64 TB (P48) SSD data storage
  • 384 GB RAM
  • Instrument control and data analysis software

Product documentation

PromethION 24 Quick Start Guide

Everything you need to install your PromethION24 and to check the system is ready for use.

2.6 MB PDF
Download

PromethION P24 device specs

PromethION 24 Technical Specification

155 KB PDF
Download

PromethION IT Requirements

This checklist represents the minimal requirements for installing the PromethION in your institution.

192 KB PDF
Download

Safety and regulatory information

110.7 KB PDF
Download

PromethION 48 Quick Start Guide

Everything you need to install your PromethION48 and to check the system is ready for use.

2.5 MB PDF
Download

PromethION P48 device specs

PromethION 48 Technical Specification

168 KB PDF
Download

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