On-farm nanopore sequencing for genomic breeding values in livestock

Harry Lamb

Harry Lamb

Abstract

Genomic selection (GS) in agriculture holds great potential to unlock the increases in productivity necessary to feed 10 billion people by 2050. Turnaround time has limited the use of traditional SNP genotyping by microarray for GS in Australia’s expansive northern beef industry. Oxford Nanopore Technologies’ MinION could provide an on-farm alternative to SNP array genotyping; allowing producers to use genomic information in real time for genomic selection. We used nanopore sequence data to simulate 50k nanopore SNP genotypes in beef cattle and calculate the accuracy of genomic breeding values at various coverages. 

Bio

Harry is a Ph.D. student working in the fields of quantitative genetics and AgTech at the Queensland Alliance for Agriculture and Food Innovation in Australia. Harry grew up on a small cattle property north of Brisbane where he developed a love for agriculture. He completed a dual Bachelor of Biotechnology and Chemical Engineering at the University of Queensland in 2019. Combining his passion for agriculture and background in science, Harry’s Ph.D. project investigates the feasibility of on-farm DNA sequencing with the MinION to predict the genetic merit of livestock.